Thursday, July 12, 2012

A NOVEL ANTIMICROBIAL PEPTIDE FROM SCORPIONS

Zeng and associates from the Department of Biotechnology, Wuhan University,  China initially reported (in 2004) type presence of  four novel peptides (BmKa1, BmKa2, BmKb1 and BmKn2) from the venom of the scorpion, Buthus martensii (Kasch). The 70 amino acid residue Peptide BmKn2 has antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, and P.aeruginosa.

A recent study, published in July PLoS ONE issue, has reported that this Peptide BmKn2 exhibited higher antibacterial activity against clinical antibiotic-resistant strains such as Methicillin-Resistant Staphylococcus aureus (MRSA).

Dr. P. Kumarasamy

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